Figure 8

Inhibition of miR-317-3p and miR-2946-3p and its effect on lifespan of adult Ae. aegypti females. (A) and (B) Effect of miRNA inhibition on relative expression of miR-317-3p in WB2.tet and WB2 mosquitoes, respectively. (C) and (D) Effect of miRNA inhibition on relative expression of miR-2946-3p in WB2.tet and WB2 mosquitoes, respectively. (E) and (F) Effect of miRNA inhibition on longevity of WB2.tet and WB2 mosquitoes, respectively. KD, knock down. WB2.tet survival was not significantly affected by miRNA inhibition. WB2 survival was significantly affected by inhibition of miR-2946-3p (Cox ph, p < 0.0001) and miR-317-3p (Cox ph, p = 0.013).