Table 9 Effect of immunosuppressive agents on the expression of MDR1 gene in UC (mean ± SD).

From: Comparison of effects of aminosalicylic acid, glucocorticoids and immunosuppressive agents on the expression of multidrug-resistant genes in ulcerative colitis

Group

Total (n)

Relative expression of MDR1

Control group

45

1.374 ± 0.022

Effective group

Pre-treatment

28

0.618 ± 0.095a

Post-treatment

28

0.523 ± 0.0201ab

Ineffective group

Pre-treatment

9

1.263 ± 0.0833d

Post-treatment

9

1.885 ± 0.054ace

  1. aP < 0.05 versus control group.
  2. bP > 0.05 versus pre-treatment.
  3. cP < 0.05 versus pre-treatment.
  4. dP < 0.05 versus effective group pre-treatment.
  5. eP < 0.05 versus effective group post-treatment.
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