Table 2 Cox-hazards ratio for univariate and multi-variate analysis for OS for dNENs. *Co-linear with Ki67 so calculated in separate multivariate model. See supplementary data.

From: Diagnostic features and management options for duodenal neuroendocrine neoplasms: a retrospective, multi-centre study

Characteristic

Univariate HR

Univariate p

Multivariate HR

Multivariate p

Age

2.62 [1.51–4.54]

p = 0.0006

1.96 [0.97–3.96]

p = 0.061

Gender

    

Female

1

   

Male

1.62 [0.49–5.38]

p = 0.434

  

Size

    

 <  = 10 mm

1

   

11-20 mm

1.34 [0.37–4.80]

p = 0.654

  

 > 20 mm

1.09 [0.21–5.54]

p = 0.916

  

Location

    

D1

1

   

D2

1.23 [0.31–4.93]

p = 0.772

  

Ki67

    

G1-2

1

 

1

 

G3

12.5 [2.38–65.2]

p = 0.003

5.10 [0.79–32.8]

p = 0.086

FDG

    

Negative

1

   

Positive

1.44 [0.15–14.2]

p = 0.753

  

68 Ga

    

Negative

1

   

Positive

0.61 [0.13–2.80]

p = 0.528

  

Functional

    

Non-functional

1

 

1

 

Functional

3.32 [0.98–11.2]

p = 0.053

2.19 [0.52–9.14]

p = 0.284

Liver mets*

    

Absent

1

 

1

 

Present

2.87 [0.92–9.00]

p = 0.071

2.16 [0.67–6.97]

p = 0.196

LN mets

    

Absent

1

   

Present

1.99 [0.63–6.29]

p = 0.239

  
Back to article page