Figure 2

Sensitivity analysis. This analysis was performed to determine the effect of differential protein expression patterns on the development of PGD3 at T48–72 h. (A) We selected 16 protein expression patterns from the pairwise comparison analysis that reached significance in at least 3 of the 12 comparisons at FDR-adjusted p < 0.25. (B) We analyzed whether these 16 expression patterns were significantly different between patients who developed PGD3 at T48–72 h. Eight of the 16 protein expression patterns were associated with PGD3 at T48–72 h at p < 0.05 and 11 of 16 at FDR-adjusted p < 0.1. (C) Boxplots for selected cytokines associated with PGD3 at T48–72 h at p < 0.05. *p < 0.05. The image was created using GraphPad Prism version 9.2 (https://www.graphpad.com/updates/prism-920-release-notes).