Table 3 Protein regulators of the four selected miRs.

From: Exosomal telomerase transcripts reprogram the microRNA transcriptome profile of fibroblasts and partially contribute to CAF formation

miR symbol

upstream regulators

References

hsa-miR-92a-3p

E2F, C Myc-↑

Oncotarget; 2020, 39: 6529–43

hsa-miR-128-3p

HIF-1α- ↑

Aging (Albany NY) 2020, 12: 4067–81 Cancer Res. 2012, 72: 6036–50

Snail- ↑

Oncotarget 2017, 8: 39,280–39,295

P53R 175H- ↑

Carcinogenesis, 2010, 31: 1045–1053

hsa-miR-342-3p

HER2Δ16- ↑

Mol Cancer 2010, 9:317

EVL (Ena/VASP-like)- ↑

Scientific Reports 2018, 8:12,252

Estrogen Receptor (ER)- ↑

Asian Pac J Cancer Prev 2012, 13: 873–7

hsa-miR-125b-1-3p

by CDX2, ↑

Summarized in: Leukemia; 2012, 26: 2011–18

NF-κβ, P53 ↑ or↓

PLoS One 2011, 6: e17169

Cell Cycle 2007, 6: 1586–93

by MYC and AKT1 ↓

Nat Genet 2008, 40: 43–50

C/EBPa- ↑

Immunity 2009, 31: 220–31

Era- ↑

Leukemia 2015, 29: 2402 – 2448

Nrf2- ↑

J. Hepatol. 2015, 63: 1466–75

 

Cell Death Differ 2015, 4: 654–64

  1. ↑ and ↓ indicate the directionality of the regulation of miR125b-1 by the various regulators.
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