Table 2 Overview of the median volume [IQR] and p-values of the normalized BCA-Features (per slice) within both endpoint categories severity and mortality.

Tissue	Sex	Severity			Mortality
Tissue	Sex	Average volume per slice [mL], mild cases	Average volume per slice [mL], severe cases	p-value	Average volume per slice [mL], survived cases	Average volume per slice [mL], deceased cases	p-value
Bone	Female	28 [4.04]	29 [3.93]	≤ 0.001	28 [4.28]	29 [4.68]	0.005
	Male	36 ± 4.21	37 ± 4.38	0.013	36 ± 4.17	37 ± 4.70	0.014
	Overall	33 [8.23]	34 [8.62]	≤ 0.001	33 [8.07]	34 [9.32]	0.104
Muscle	Female	49 [13.12]	44 [15.81]	≤ 0.001	49 [13.71]	40 [13.51]	≤ 0.0001
	Male	73 [26.37]	69 [25.59]	0.018	74 [27.16]	62 [21.74]	≤ 0.0001
	Overall	62 [29.24]	60 [29.85]	0.057	63 [30.30]	53 [25.27]	≤ 0.0001
IMAT	Female	20 [9.59]	21 [11.09]	0.032	20 [9.57]	21 [11.24]	0.079
	Male	18 [10.84]	22 [11.32]	≤ 0.0001	19 [10.87]	22 [10.61]	≤ 0.001
	Overall	19 [10.39]	22 [11.40]	≤ 0.0001	19 [10.53]	22 [10.80]	≤ 0.001
EAT	Female	1 [1.29]	1 [1.50]	0.709	1 [1.22]	2 [1.65]	0.201
	Male	2 [1.57]	2 [1.66]	≤ 0.001	2 [1.48]	2 [1.70]	0.011
	Overall	2 [1.46]	2 [1.55]	≤ 0.001	2 [1.44]	2 [1.65]	0.008
PAT	Female	3 [3.0]	4 [2.95]	0.047	4 [2.87]	4 [3.45]	0.075
	Male	6 [4.60]	7 [4.21]	≤ 0.0001	6 [4.45]	7 [4.53]	0.003
	Overall	5 [4.39]	6 [4.77]	≤ 0.0001	5 [4.37]	6 [4.97]	0.006

Only the male average bone volume per slice was normally distributed and thus is reported as mean and SD. The p-values were calculated using the Mann–Whitney-U test IMAT: intra- and intermuscular adipose tissue, EAT: epicardial adipose tissue, PAT: pericardial adipose tissue.

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