Table 1 Baseline characteristics of the study participants.

Males/females^a

41/36 (53.2/46.8)

24/27 (47.1/52.9)

65/63 (50.8/49.2)

0.61

Age^b

7.8 (2.4)

15.1 (1.7)

10.7 (4.2)

< 0.001

Stomatological and dental findings

Caries^a

38 (49.4)

11 (21.6)

49 (38.3)

0.003

Gingivitis^a

14 (18.2)

21 (41.2)

35 (27.3)

0.008

Washable plaque^a

51 (66.2)

21 (41.2)

72 (56.2)

0.009

Xerostomia^a

0 (0)

0 (0)

0 (0)

n.e

Candidiasis^a

0 (0)

1 (2)

1 (0.8)

0.40

Decayed teeth^c

0.5 (0, 3)

0 (0, 0)

0 (0, 1.5)

0.001

Missing teeth^c

0 (0, 1)

0 (0, 0)

0 (0, 0.5)

0.080

Filled teeth^c

2 (0, 5)

1 (0, 3)

2 (0, 4)

0.27

Any mucosal changes^a

4 (5.2)

2 (3.9)

6 (4.7)

1

Aphthae^a

2 (2.6)

0 (0)

2 (1.6)

0.52

Saliva total quantity (ml)^c

3.2 (2.1, 4.7)

6.0 (4.0, 10.7)

4.2 (2.6, 6.5)

< 0.001

Salivary flow rate (ml/min)^b

0.8 (0.5)

1.5 (0.8)

1.0 (0.7)

< 0.001