Figure 7 | Scientific Reports

Figure 7

From: Chitosan oligosaccharide alleviates renal fibrosis through reducing oxidative stress damage and regulating TGF-β1/Smads pathway

Figure 7

The effects of COS on the oxidative stress injury indicators and expression level of TGF-β/Smads signaling pathway protein from kidney tissues in UUO-induced renal fibrosis mice. SOD levels (A). GSH levels (B). GSH-Px levels (C). MDA levels (D). Representative Western blot analysis bands of TGF-β/Smads signaling pathway protein (E). Quantitative statistical chart from western blot analysis of p-Smad2/Smad2 and p-Smad3/Smad3 proteins (F). Quantitative statistical chart from western blot analysis of TGF-β1, Smad7 and Smad4 proteins (G). The original bands of Western blot from (E) were shown in the Supplementary Fig. S1. All values are represented as mean ± SD (n = 10 in each group). Superscript letters a and b designate significant differences. aP < 0.05 compared with the model group. bP < 0.01 compared with the model group.

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