Table 1 Comparison between histomorphologic and radiologic features according to the stromal component of chordomas.

From: Differences in stromal component of chordoma are associated with contrast enhancement in MRI and differential gene expression in RNA sequencing

Variables

Stroma-poor (n = 20)

Stroma-rich (n = 25)

p-value

Histology (n, %)

Nuclear pleomorphism

4 (20.0%)

7 (28.0%)

0.729*

Necrosis

2 (10.0%)

1 (4.0%)

0.577*

BNCT-like component

13 (65.0%)

1 (4.0%)

 < 0.001

Cellularity (%)

90 (IQR 72.5–90.0)

40 (IQR 20–60)

 < 0.001§

Imaging (n, %)

T2 signal intensity

1.000*

 High

16 (80.0%)

21 (84.0%)

 

 Intermediate

4 (20.0%)

4 (16.0%)

 

T2 signal homogeneity

0.182

 Homogeneous

12 (60.0%)

10 (40.0%)

 

 Heterogeneous

8 (40.0%)

15 (60.0%)

 

Enhancement, presence

8 (40.0%)

21 (84.0%)

0.002

  1. BNCT benign notochordal cell tumor, IQR Interquartile range.
  2. *Fisher’s exact test.
  3. §Mann–Whitney test.
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