Figure 6

The number of PPIs per sample (x-axis) was positively correlated with the number of indirect connections per protein for (A) chromosomal (red, r = 0.61) but not all proteins (including plasmid-encoded ones, blue, r = 0.02) in the 489 samples with plasmid-encoded proteins. (B) The other samples with no plasmid-encoded proteins had positive correlations (green, r = 0.63 and r = 0.67) though with a bimodal pattern (groups of n = 2415 and n = 1336). The lines of best fit for each plot shows the linear correlation of the number of PPIs per sample with the number of indirect connections per protein. The histograms indicate the marginal densities per axis for each dataset.