Figure 8
From: Reduction of stress responses in honey bees by synthetic ligands targeting an allatostatin receptor
Effects of B5 and B6 compounds on ASTA signaling in vitro. Relative levels of forskolin-induced intracellular cAMP (expressed as percentages of control levels, i.e. with forskolin only). Treatment with ASTA significantly decreased cAMP levels, which was reversed when either B5 (a) or B6 (b) was added (albeit not significantly with 56.5 μM B6). ##: p < 0.01 (vs. forskolin only); *: p < 0.05; ***: p < 0.0005 (vs. forskolin + ASTA) (at least 5 replicates per combination).
