Table 1 Cardiac functions of Runx2fl/fl and Runx2 CKO mice after MI.

From: Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling

 

Day0

Day7

Day14

fl/fl

CKO

fl/fl

CKO

fl/fl

CKO

LVIDd (cm)

0.37 ± 0.02

0.37 ± 0.02

0.43 ± 0.03

0.47 ± 0.08

0.48 ± 0.02††

0.50 ± 0.05††

LVIDs (cm)

0.17 ± 0.01

0.17 ± 0.02

0.25 ± 0.02

0.30 ± 0.08

0.31 ± 0.01††

0.36 ± 0.03*††

FS (%)

54.0 ± 3.1

53.2 ± 2.8

41.9 ± 3.7

37.4 ± 5.1

34.7 ± 4.5††

29.0 ± 2.8*††

  1. LVIDd = left ventricular internal dimension at diastole; LVIDs = left ventricular internal dimension at systole; FS = fractional shortening. Data are shown as mean ± SD (Runx2fl/fl mice: n = 5, Runx2 CKO mice: n = 6). *P < 0.05 vs Runx2fl/fl at Day14 by Student’s t-test, ††P < 0.01 vs Day0 by Dunnett test.