Table 1 Demographic Data of 5601 Nodules in This Study.

From: Malignancy risk stratification of thyroid nodules according to echotexture and degree of hypoechogenicity: a retrospective multicenter validation study

Nodules

Total (N = 5601)

Benign (N = 4512)

Malignant (N = 1089)

P

Number of patients

4989

3991

998

 

Age (years)

53.4 ± 12.7

54.6 ± 13.1

48.8 ± 13.9

 < .001

No. of female patients (%)

4627 (82.6%)

3793 (84.1%)

834 (76.6%)

 < .001

Mean maximal nodule size (mm)

20.7 ± 10.8

21.1 ± 10.7

19.1 ± 11.1

 < .001

US echotexture of nodules

 < .001

Homogeneous

4274 (76.3%)

3492 (77.4%)

782 (71.8%)

 

Heterogeneous

1327 (23.7%)

1020 (22.6%)

307 (28.2%)

 

US echogenicity of nodulesa

 < .001

Marked hypoechogenicity

315 (5.6%)

111 (2.5%)

204 (18.7%)

 

Moderate hypoechogenicity

705 (12.6%)

365 (8.1%)

340 (31.2%)

 

Mild hypoechogenicity

994 (17.7%)

760 (16.8%)

234 (21.5%)

 

Iso- or hyperechogenicity

3587 (64.0%)

3276 (72.6%)

311 (28.6%)

 
  1. Unless otherwise indicated, data are numbers with percentages in parentheses for categorical variables.
  2. aDetermined by the predominant echogenicity in nodules with heterogeneous echotexture.