Table 4 Malignancy risk of four nodule categories based on composition and predominant echogenicity.

From: Malignancy risk stratification of thyroid nodules according to echotexture and degree of hypoechogenicity: a retrospective multicenter validation study

 

Solid hypoechoic

Partially cystic hypoechoic

Solid isoechoic

Partially cystic isoechoic

No. of malignant nodules/all

Malignancy risk (95% CI)

No. of malignant nodules/all

Malignancy risk (95% CI)

No. of malignant nodules/all

Malignancy risk (95% CI)

No. of malignant nodules/all

Malignancy risk (95% CI)

All

705/1560

45.2 (41.9, 48.7)

73/454

16.1 (12.6, 20.2)

192/1481

13.0 (11.2, 14.9)

119/2106

5.7 (4.7, 6.8)

P

 < .001a

0.122b

 < .001c

Any suspicious feature

536/780

68.7 (63.0, 74.8)

41/134

30.6 (22.0, 41.5)

93/300

31.0 (25.0, 38.0)

40/294

13.6 (9.7, 18.5)

P

 < .001a

0.954b

 < .001c

No suspicious feature

169/780

21.7 (18.5, 25.2)

32/320

10.0 (6.8, 14.1)

99/1181

8.4 (6.8, 10.2)

79/1812

4.4 (3.5, 5.4)

P

 < .001a

0.385b

 < .001c

  1. aSolid hypoechoic versus partially cystic hypoechoic.
  2. bPartially cystic hypoechoic versus Solid isoechoic.
  3. cSolid isoechoic versus partially cystic isoechoic.