Table 1 Predicted, promiscuous and totally conserved CD4+ and CD8+ epitopes of highest affinity.
Protein | Amino acids | CD4+ total epitopes | CD4+ overlapping epitopes | CD8+ total epitopes | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Predicted | % | Alleles bound | Predicted | % | Alleles bound | Predicted | % | Alleles bound PR < 1% | Alleles bound PR < 0.5% | ||
E | 75 | 25 | 3.7 | 14–21 | 6 | 4.4 | 14–19 | 2 | 4.3 | 10 | 7 |
M | 222 | 30 | 4.4 | 14–22 | 5 | 3.7 | 14–22 | 1 | 2.1 | 10 | 9 |
N | 419 | 7 | 1.0 | 14–16 | 2 | 1.5 | 14–16 | 2 | 4.3 | 10–13 | 6–9 |
ORF1ab | 7096 | 537 | 79.4 | 14–26 | 100 | 74.1 | 14–23 | 36 | 76.6 | 10–15 | 4–11 |
ORF6 | 61 | 25 | 3.7 | 14–22 | 7 | 5.2 | 14–20 | 0 | 0.0 | – | – |
ORF7b | 43 | 9 | 1.3 | 14–18 | 2 | 1.5 | 15–16 | 0 | 0.0 | – | – |
ORF8 | 121 | 2 | 0.3 | 15–16 | 1 | 0.7 | 15 | 1 | 2.1 | 10 | 7 |
S | 1273 | 41 | 6.1 | 14–19 | 12 | 8.9 | 14–19 | 5 | 10.6 | 11–12 | 2–8 |
