Figure 4 | Scientific Reports

Figure 4

From: Imperatorin exerts antioxidant effects in vascular dementia via the Nrf2 signaling pathway

Figure 4

The effect of IMP on the apoptosis rate of CoCl2-induced hypoxia hippocampal neuronal cells. In the figure, the upper left quadrant is dead cells (Q1), the upper right quadrant is late apoptotic cells (Q2), the lower right quadrant is early apoptotic cells (Q3), and the lower left quadrant is living cells (Q4). The total number of apoptotic cells is the sum of Q2 + Q3. (A) Normal group, (B) CoCl2 treatment group, (C) CoCl2 + 5.0 μmol/l IMP, (D) CoCl2 + 7.5 μmol/l IMP, (E) CoCl2 + 10.0 μmol/l IMP. (n = 6 for every group,, **P < 0.01, ***P < 0.01, ****P < 0.0001).

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