Figure 6
From: Imperatorin exerts antioxidant effects in vascular dementia via the Nrf2 signaling pathway
The effect of IMP on the nuclear translocation of Nrf2 protein in CoCl2-induced hypoxia in hippocampal neuronal cells (× 400). Red fluorescence is positive staining for Nrf2 protein, indicating the expression of Nrf2 protein, and blue fluorescence is DAPI staining, indicating cell nucleus. Emerge image is a fusion image of Nrf2 protein and cell nucleus for positioning. The Zoom image is a magnified image randomly selected from the emerge image to observe the Nrf2 positioning. (A) Normal group, (B) CoCl2 treatment group, (C) CoCl2 + 5.0 μmol/l IMP, (D) CoCl2 + 7.5 μmol/l IMP, (E) CoCl2 + 10.0 μmol/l IMP.
