Figure 3

Network meta-analysis results for the primary outcomes. All-cause mortality, severe NEC (stage 2 or more)—top table, and late-onset sepsis—lower table. Results are odds ratio and their corresponding 95% CI. The table should be read from left to right. For all-cause mortality (bottom part of the table), an OR > 1.0 means an increase in mortality. For NEC stage ≥ II (upper part of the table), an OR < 1.0 means a reduction in developing NEC. For culture-proven late-onset sepsis (inferior table), an OR < 1.0 means a reduction in sepsis. Significant results are presented in bold and underlined. The colours represent the GRADE certainty of evidence: green: high; light green: moderate; light orange: low; and orange: very low. *For NEC and sepsis, results are from the fixed-effect model. i.v. intravenous, NAC N-acetyl cysteine, NEC necrotizing enterocolitis.