Figure 4
Bowel dysfunction confounds relationships linking ASD to differential bacterial taxa abundances. Taxa significantly associated with NT (positive direction) or ASD (negative direction) by meta-analysis are plotted by phylum. Taxonomic label prefixes indicate the taxon’s rank where t__, s__, g__ or f__ are strain, species, genus or family, respectively. ASD-associated signatures are different when children with bowel dysfunction are included (left panels) compared to when only children with normal bowel function are considered (right panels). Missing data points indicate taxa absent from the remaining datasets and individuals. Effect sizes and significance were calculated using random-effects models.
