Table 1 Summary of datasets.

From: Multi-angle meta-analysis of the gut microbiome in Autism Spectrum Disorder: a step toward understanding patient subgroups

Dataset

Publication

Technology

Sequencing instrument

16S region

ASD (n)

NT (n)

Minimum age (years)

Maximum age (years)

Median age (years)

Male (%)

DS1

Kang et al. 2013

16S HTS

454 Genome Sequencer FLX Titanium

V2V3

20

20

3

16

6

87.5

DS2

Kang et al. 2018

16S HTS

454 Genome Sequencer FLX Titanium

V2V3

23

21

4

17

9

84.1

DS3

Kang et al. 2017

Kang et al. 2019

16S HTS

Illumina MiSeq

V4

18

20

7.1

16.7

11.05

89.5

DS4

Li et al. 2019

16S HTS

Illumina HiSeq

V1V2

59

30

2

10

Not reported

Not reported

DS5

Strati et al. 2017

16S HTS

454 Genome Sequencer FLX

V3V5

39

39

Not reported

Not reported

Not reported

Not reported

DS6

Coretti et al. 2018

16S HTS

Illumina MiSeq

V3V4

11

14

2

4

Not reported

Not reported

DS7

Wang et al. 2019

MTG

Illumina HiSeq 4000

43

31

2

8

4

73.0

DS8

Pulikkan et al. 2018

16S HTS

Illumina NextSeq 500

V3

29

24

3

16

9

75.5

DS9

Averina et al. 2020

MTG

Illumina HiSeq 4000

29

20

2

9

3

79.6

DS10

16S HTS

Illumina MiSeq

V3V4

15

5

2

9

3.5

70.0

DS11

Internal

16S HTS

Illumina MiSeq

V4

107

92

2

11.83

4.75

72.4

DS12

PhyloChip

Thermo-Fisher Gene Titan

V1V9

96

93

2

11.83

5.17

72.0

DS13

MTG

Illumina NextSeq

96

91

2

11.83

5.17

73.3

  1. HTS high-throughput sequencing, MTG metagenomics.