Figure 2

Dynamics of S. aureus abundance in nasal samples of carriers and noncarriers undergoing decolonization. Shown are S. aureus abundance in quantitative culture (CFU/ml on a log scale; A) and proportion in 16S RNA metabarcoding (B) through time in 8 carriers (red) and 8 noncarriers (blue). D0 and D7 denote samples taken immediately before and after the decolonization procedure, respectively. Dashed lines denote each participant’s data. Solid lines and colored band denote the mean and 95% confidence interval. Both culture and metabarcoding analysis identified a sharp decrease of S. aureus abundance after decolonization followed by recolonization. On average, post-decolonization abundance of S. aureus was less than before decolonization.