Figure 8

(A) Differential expression of three DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B). (B) Methylation was evaluated using UALCAN. (C) The methylation site of PLAU DNA sequence association with gene expression was visualized using MEXPRESS. The top 4 most significant methylation sites are marked and were negatively correlated with PLAU expression. *p < 0.05, **p < 0.01, ***p < 0.001.