Figure 3

Age dependence of spontaneous neuropathology in Tg20 mice challenged with D-PBS or buffer. The proportion of Tg20 mice affected by neuropathological changes of all types (with patterns A, B and C) are shown as a percentage of the total number of mice examined in each of the age cohorts indicated on the x-axis. The numbers of mice affected were; < 500 days 0/3, 501–600 days 1/10, 601–700 days 7/18, 701–800 days 12/17 and > 801 days 5/6.