Table 1 Non-synonymous (dN) and synonymous (dS) substitution rates at the MHC class II DQB exon 2.

From: Intronic primers reveal unexpectedly high major histocompatibility complex diversity in Antarctic fur seals

 

dN

dS

HA: dN ≠ dS

HA: dN > dS

Z

p

Z

p

Exon

0.41 ± 0.09

0.06 ± 0.03

3.194

0.002

3.077

0.001

pABS

0.78 ± 0.18

0.00 ± 0.00

4.064

 < 0.001

4.154

 < 0.001

Non-pABS

0.23 ± 0.08

0.08 ± 0.04

0.991

0.324

0.985

0.163

  1. p-values highlighted in bold indicate significant Z-statistics supporting the tested hypotheses based on modified Nei–Gojobori models with Jukes-Cantor correction. pABS putative antigen binding sites.
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