Table 2 Diaphragmatic thickness and excursion measured by ultrasound in three groups.

From: Quantification of diaphragmatic dynamic dysfunction in septic patients by bedside ultrasound

 

Raw diaphragmatic parametera

Adjusted model (least-square mean, 95% CI)b

P for trendc

Control (n = 107)

Sepsis1 (n = 41)

Sepsis2 (n = 33)

Control (n = 107)

Sepsis1 (n = 41)

Sepsis2 (n = 33)

Thickness(cm)

1.96(1.79–2.11)

2.09(1.83–2.30)

1.98(1.83–2.15)

1.96(1.79–2.11)

2.09(1.84–2.30)

1.98(1.83–2.14)

0.65

TF (%)

68(60–77)

46(39–55)

20(17–25)

68(60–77)

46(39–54)*

20(18–24)*†

 < 0.0001

Excursion (mm)

Quiet breathing

16.41 ± 3.92

15.31 ± 3.74

10.33 ± 2.49

16.19(15.09- 17.29)

14.84(13.46–16.21)

10.14(8.78–11.51)*†

 < 0.0001

Deep breathing

42.26 ± 8.21

27.46 ± 6.03

16.27 ± 4.76

41.66(39.46–43.86)

27.14(24.41–29.88)*

16.01(13.30–18.72)*†

 < 0.0001

EQB/EDB

0.38(0.34–0.46)

0.56(0.50–0.62)

0.67(0.58–0.70)

0.40(0.37–0.43)

0.56(0.52–0.60)*

0.66(0.62–0.69)*†

 < 0.0001

  1. The above analyses were adjusted for sex, age, BMI, MAP, hypertension and diabetes, rather than using the raw data of diaphragmatic parameters directly.
  2. *P < 0.05 compared with control group; †P < 0.05 compared with sepsis group 1.
  3. aAll raw data was presented as median (IQR) or mean ± SD for continuous variables.
  4. bThe adjusted least-square mean and 95% CI were calculated by covariance analysis (CI = confidence interval).
  5. cP for trend of diaphragmatic ultrasound parameters across sepsis severity were calculated based on generalized linear models.
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