Figure 2 | Scientific Reports

Figure 2

From: Serpin-positive Bifidobacterium breve CNCM I-5644 improves intestinal permeability in two models of irritable bowel syndrome

Figure 2

Immunomodulatory properties of probiotic strains on human PBMCs from five donors. (a) IL-10/IL-12 ratio after incubation of strains with PBMCs. (b) IL-10 immunomodulation after incubation of strains with PBMCs. Cytokines were quantified by ELISA after co-incubation of bacteria and PBMCs from five donors for 48 h. Data are presented as mean (n = 15) ± SEM. A one-way ANOVA test was performed followed by a Dunnet’s test to compare treated groups with RPMI medium group. *p < 0.05, **p < 0.001.

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