Table 4 Bivariate regression and multivariate regression analysis results for the risk factors of organ-space SSIs.

From: The role of preoperative albumin and white blood cell count in surgical site infections following whipple surgery

Variables

uOR

95% CI for uOR

aOR

95% CI for aOR

p-value for aOR

Agea (years)

1.00

0.99–1.00

 −   

 −  

 −  

Female

0.74

0.69–0.80

0.79

0.73–0.85

 < 0.001

BMI (kg/m2)

1.03

1.03–1.04

1.04

1.03–1.04

 < 0.001

Racial minority

0.85

0.78–0.92

1.30

1.19–1.42

 < 0.001

DM

0.86

0.79–0.93

0.79

0.73–0.87

 < 0.001

Steroid use for chronic disease

1.2

0.97–1.48

 −   

 −   

 −   

Hypertension

1.10

1.02–1.18

 −   

 −   

 −   

Smoking

0.83

0.75–0.91

0.86

0.77–0.94

0.002

Disseminated cancer

1.30

1.10–1.52

1.29

1.10–1.52

0.002

> 10% weight loss in last 6 months

0.76

0.68–0.84

0.85

0.77–0.95

0.004

Bleeding disorders

1.40

1.14–1.71

1.40

1.14–1.72

0.001

Systemic sepsis

1.40

1.08–1.81

1.36

1.04–1.78

0.027

Serum albumin < 3.73 (g/dL)

1.10

1.02–1.19

 −   

 −   

 −   

Serum sodium (mmol/L)

1.03

1.02–1.04

1.02

1.01–1.03

0.002

Serum BUN (mg/dL)

1.01

1.00–1.01

1.01

1.00–1.01

0.02

WBC count (/m3)

1.02

1.01–1.03

1.02

1.01–1.03

0.012

HCT (%)

1.03

1.02–1.04

1.03

1.02–1.03

 < 0.001

Wound classification (clean-contaminated)

1.20

1.11–1.29

1.20

1.11–1.29

 < 0.001

Operative time (hours)

1.00

1.00–1.00

1.04

1.02–1.06

 < 0.001

Pylorus sparing procedure

0.85

0.79–0.91

0.91

0.85–0.98

0.011

  1. Variables dropped from the model due to insignificance at the multivariate level: preoperative serum albumin, steroid use for chronic condition, age and hypertension.
  2. SSI surgical site infection, uOR unadjusted odds ratio, aOR adjusted odds ratio, CI confidence interval, BMI body mass index, DM diabetes mellitus, BUN blood urea nitrogen, HCT hematocrit, WBC white blood cells.
  3. aWith patients over 89 coded as 90+.
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