Table 2 Risk of stroke, myocardial infarction, and mortality according to acute pancreatitis history.

From: Risk of cardiovascular disease and mortality in patients with diabetes and acute pancreatitis history: a nationwide cohort study

AP history

N

Event

Incidence rate, /1,000 person-yr

Hazard ratio (95% confidence interval)

Model 1

Model 2

Model 3

Model 4

Model 5

  

Stroke

      

No

2,067,549

72,092

4.82

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Yes

3,810

217

8.90

1.858 (1.626,2.123)

1.858 (1.626,2.122)

1.748 (1.53,1.997)

1.731 (1.515,1.978)

1.534 (1.342,1.753)

  

MI

      

No

2,067,549

47,377

3.15

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Yes

3,810

192

7.86

2.549 (2.212,2.937)

2.495 (2.165,2.875)

2.304 (1.999,2.655)

2.287 (1.984,2.635)

1.998 (1.733,2.303)

  

Mortality

      

No

2,067,549

153,400

10.11

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Yes

3,810

871

34.88

3.500 (3.274,3.741)

3.335 (3.12,3.564)

3.087 (2.888,3.299)

2.860 (2.676,3.057)

2.353 (2.200,2.515)

  1. Model 1, unadjusted; Model 2, adjusted for age and sex; Model 3, adjusted for model 2 + smoking, alcohol drinking, regular exercise, and income level; Model 4, adjusted for model 3 + hypertension, dyslipidemia, and body mass index; Model 5, adjusted for model 4 + diabetes duration, use of insulin, and prescription of two or more oral diabetic agents.
  2. AP acute pancreatitis; MI, myocardial infarction.