Table 2 Multivariate analysis of risk factors for AKI in patients receiving ICIs.

From: Incidence, risk factors and prognosis of acute kidney injury in patients treated with immune checkpoint inhibitors: a retrospective study

Risk factors

OR

95% CI

P value

eGFR (mL/min·1.73m2)

1

0.99–1.01

0.4069

Anemia

1.95

1.16–3.28

0.0123

Alb < 30 g/L

1.62

1.17–2.23

0.0034

30 g/L ≤ Alb ≤ 35 g/L

0.58

0.32–1.09

0.0914

ACEI/ARB

0.25

0.06–1.13

0.0731

Antibiotics

2.56

1.10–5.95

0.0288

Diuretics

1.75

1.12–2.73

0.0132

NSAIDs

3.12

1.96–4.97

 < 0.001

PPI

2.07

1.17–3.66

0.0124

Nivolumab

1.20

0.78–1.87

0.4096

Toripalimab

0.44

0.04–5.33

0.5226

Sintilimab

0.53

0.27–1.03

0.0626

Extrarenal irAEs

1.53

0.63–3.72

0.3453

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