Table 1 MIC and FICI values for PRE and Zn (II) alone and in combination against C. albicans (ATCC 90028), determined by broth dilution and checkerboard method.
MIC | MIC in combination | FIC | FICI | |
---|---|---|---|---|
PRE (mg/mL) | 4 ± 1.8 | 0.25 ± 0.115 | 0.0625 ± 0.03 | – |
Zn (II) (mg/mL) | 1.8 ± 0.75 | 0.112 ± 0.05 | 0.0625 ± 0.03 | – |
PRE + Zn (II) | – | – | 0.125 ± 0.05 (synergism) |