Table 1 MIC and FICI values for PRE and Zn (II) alone and in combination against C. albicans (ATCC 90028), determined by broth dilution and checkerboard method.

From: Synergistic activity of pomegranate rind extract and Zn (II) against Candida albicans under planktonic and biofilm conditions, and a mechanistic insight based upon intracellular ROS induction

 

MIC

MIC in combination

FIC

FICI

PRE (mg/mL)

4 ± 1.8

0.25 ± 0.115

0.0625 ± 0.03

Zn (II) (mg/mL)

1.8 ± 0.75

0.112 ± 0.05

0.0625 ± 0.03

PRE + Zn (II)

 

0.125 ± 0.05 (synergism)