Figure 6

CellMap predictions on bulk RNA-seq data from iPSC-derived cell types and ROSMAP brain samples. (a) Time course of iPSC-derived cardiomyocytes from GSE122380. (b) Multiple treatments of iPSC-derived Microglia. (c,d) Comparing five batches of iPSC derived NGN2 neurons. DIV - days in vitro. (e,f) Sample composition predictions for ROSMAP samples relative to composition measured by IHC and snRNA-seq. Error bars represent the standard deviations across samples for each cell type. (g) Composition RMSE values of CellMap predictions across the 9 cell types and all ROSMAP samples compared to the compositions derived from IHC and snRNA-seq data.