Figure 6 | Scientific Reports

Figure 6

From: Inhibition of Rho/ROCK signaling pathway participates in the cardiac protection of exercise training in spontaneously hypertensive rats

Figure 6

Effect of exercise training on expression of RhoA and ROCK. (A) Representative blot images of RhoA and ROCK proteins. (C,D) Expression of RhoA and ROCK mRNA. (E,F) Expression of RhoA and ROCK proteins. SHR-Sed SHR control group, WKY-Sed WKY control group, SHR-ExT SHR exercise group, WKY-ExT WKY exercise group, SHR-ExT-LPA SHR exercise plus LPA group; SHR-Fasudil SHR plus Fasudil group; data are expressed as mean ± SEM. n = 3 in each group. #P < 0.05, ##P < 0.01 vs WKY-Sed; $P < 0.05, $$P < 0.01 vs SHR-ExT; *P < 0.05, **P < 0.01 vs SHR-Sed. (B) Representative confocal photomicrographs of ROCK-stained and DAPI-stained left ventricular sections. Green fluorescence shows ROCK-positive cells; blue fluorescence shows the nuclei of cardiomyocytes (DAPI-positive). Scale bar = 50 μm.

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