Table 5 Association between previous DENV/ZIKV exposure and severe dengue* during the current DENV infection.

From: Effect of prior Zika and dengue virus exposure on the severity of a subsequent dengue infection in adults

Anti-DENV/ZIKV IgG sero-status

Severe dengue

Risk ratio (95% CI)

P value**

No

Yes

Prior DENV and ZIKV exposure

103

8

Not calculated

0.002

No exposure to both infections

133

0

Prior DENV exposure only

163

16

Not calculated

 < 0.001

No exposure to both infections

133

0

Prior DENV and ZIKV exposure

103

8

0.81 (0.36–1.82)

0.667

Prior DENV exposure only

163

16

  1. *Define according to WHO 2009 clinical classification of dengue.
  2. **Calculated as two-tailed p value with Fisher’s exact test.
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