Table 3 Cutoff points and diagnostic values of ferritin test for any grade of liver hemosiderosis (n = 400).

From: Ferritin thresholds for cardiac and liver hemosiderosis in β-thalassemia patients: a diagnostic accuracy study

Cutoff points

Sensitivity,%

95% CI

Specificity,%

95% CI

PPV,%

95% CI

NPV,%

95% CIs

 > 900

69.78

63.3–75.7

58.76

48.3–68.7

79.7

73.4–85.1

45.6

36.7–54.7

 > 1000

68.00

61.5–74.0

64.95

54.6–74.4

81.8

75.5–87.1

46.7

38.0–55.4

 > 1090

66.67

60.1–72.8

68.04

57.8–77.1

82.9

76.6–88.1

46.8

38.4–55.4

 > 1200

61.33

54.6–67.7

70.10

60.0–79.0

82.6

76.0–88.1

43.9

35.9–52.1

 > 1300

57.33

50.6–63.9

71.13

61.0–79.9

82.2

75.3–87.8

41.8

34.2–49.7

 > 1400

53.33

46.6–60.0

72.16

62.1–80.8

81.6

74.4–87.5

40.0

32.7–47.7

 > 1500

48.00

41.3–54.7

72.16

62.1–80.8

80.0

72.3–86.4

37.4

30.5–44.8

 > 1600

46.22

39.6–53.0

73.20

63.2–81.7

80.0

72.1–86.5

37.0

30.1–44.2

 > 1700

43.56

37.0–50.3

76.29

66.6–84.3

81.0

72.9–87.6

36.8

30.1–43.9

 > 1800

42.22

35.7–49.0

77.32

67.7–85.2

81.2

72.9–87.8

36.6

30.0–43.6

 > 1900

39.11

32.7–45.8

80.41

71.1–87.8

82.2

73.7–89.0

36.3

29.8–43.1

 > 2000

35.56

29.3–42.2

83.51

74.6–90.3

83.3

74.4–90.2

35.8

29.6–42.5

 > 2102

34.67

28.5–41.3

85.57

77.0–91.9

84.8

75.8–91.4

36.1

29.9–42.7

 > 2200

34.22

28.0–40.8

86.60

78.2–92.7

85.6

76.6–92.1

36.2

30.0–42.8

 > 2300

32.89

26.8–39.4

87.63

79.4–93.4

86.0

76.9–92.6

36.0

29.9–42.5

 > 2400

31.56

25.5–38.1

89.69

81.9–94.9

87.7

78.5–93.9

36.1

30.0–42.5

 > 2500

29.33

23.5–35.8

91.75

84.4–96.4

89.2

79.8–95.2

35.9

29.9–42.2

  1. The best cutoff point (ng/mL) based on empirical cutoff point estimation (Youden method) was > 1090.