Figure 4

Progression-free survival (PFS) and overall survival (OS) according to the combination of peripheral T cell cytotoxicity and the peripheral CD45RA+CD25+/CD4+ T cell ratio. (A) Kaplan–Meier curves for the PFS of patients according to the CD45RA+CD25+/CD4+ T cell ratio. (B) Kaplan–Meier curves for the OS of patients according to the CD45RA+CD25+/CD4+ T cell ratio. (C) Kaplan–Meier curves for the PFS of patients with peripheral T cell cytotoxicity ≥ 17% according to the CD45RA+CD25+/CD4+ T cell ratio. (D) Kaplan–Meier curves for the OS of patients with peripheral T cell cytotoxicity ≥ 17% according to the CD45RA+CD25+/CD4+ T cell ratio. The significance of differences was assessed using the Log-rank test (A–D).