Table 1 Baseline characteristics for the study population.
Characteristic | All | Eventa | No event | p value | |||
---|---|---|---|---|---|---|---|
Number, n (%) | 783 | 45 | (6) | 738 | (94) | – | |
Age, years | 55 | (43–64) | 60 | (53–66) | 54 | (42–64) | 0.005 |
Female sex, % | 342 | (44) | 24 | (47) | 321 | (43) | 0.74 |
CMR characteristics | |||||||
ECV, % | 27.6 | (25.3–30.3) | 30.3 | (28.3–33.6) | 27.5 | (25.1–30.1) | < 0.001 |
Native myocardial T1 | 999 | (966–1038) | 1031 | (1002–1070) | 998 | (966–1035) | < 0.001 |
EDV, mL | 160.7 | (130.8–205.5) | 190.6 | (154.0–254.0) | 159.7 | (129.7–204.0) | 0.007 |
EDVI, mL/m2 | 78.3 | (66.1–97.3) | 94.0 | (75.5–125.6) | 77.8 | (65.6–95.3) | < 0.001 |
GLS, % | − 16.2 | (− 18.8 to − 12.3) | − 10.2 | (− 15.9 to − 6.9) | − 16.3 | (− 19.0 to − 12.7) | < 0.001 |
LVEF, % | 58.5 | (47.0–65.0) | 47.0 | (23.0–63.0) | 59.0 | (48.0–65.0) | < 0.001 |
LVM, g | 113.0 | (88.1–145.6) | 127.7 | (87.3–151.9) | 112.0 | (88.2–144.2) | 0.24 |
LVMI, g/m2 | 55.3 | (44.9–67.1) | 62.5 | (46.8–73.7) | 54.5 | (44.9–67.0) | 0.07 |
BMI, kg/m2 | 28.6 | (24.4–33.9) | 29.0 | (24.0–35.9) | 28.6 | (24.4–33.8) | 0.80 |
BSA, m2 | 2.0 | (1.8–2.2) | 2.0 | (1.8–2.2) | 2.0 | (1.8–2.2) | 0.35 |
Infarct, n | 165 | (21) | 19 | (42) | 146 | (20) | < 0.001 |
Infarct sizeb, % | 14.7 | (5.9–22.6) | 22.1 | (12.9–25.0) | 14.0 | (5.9–21.3) | 0.11 |
Non-ischemic scar, n | 137 | (17) | 10 | (22) | 127 | (17) | 0.39 |
Non-ischemic scar sizeb, % | 2.9 | (1.5–5.7) | 2.6 | (1.9–5.1) | 2.9 | (1.3–5.7) | 0.72 |
ECG characteristics | |||||||
QTc, ms | 437 | (419–459) | 462 | (442–474) | 436 | (418–457) | < 0.001 |
Frontal QRS-T angle, degrees | 30 | (14–61) | 77 | (33–123) | 29 | (13–56) | < 0.001 |
Comorbidity, n (%) | |||||||
Hypertension | 398 | (51) | 33 | (73) | 365 | (50) | 0.002 |
Diabetes mellitus | 171 | (22) | 24 | (53) | 147 | (20) | < 0.001 |
Dyslipidemia | 303 | (39) | 24 | (53) | 279 | (38) | 0.04 |
CAD (obstructive) | 139 | (18) | 16 | (35) | 123 | (17) | 0.001 |
CABG | 59 | (8) | 10 | (22) | 49 | (7) | < 0.001 |
Previous percutaneous coronary intervention | 94 | (12) | 7 | (16) | 87 | (12) | 0.45 |
Heart failure | 194 (25) | 28 | (62) | 166 | (22) | < 0.001 | |
Smoking status, n (%) | |||||||
Current smoker | 129 | (17) | 12 | (27) | 117 | (16) | 0.06 |
Ex-smoker | 246 | (31) | 16 | (36) | 230 | (30) | 0.54 |
General indication for CMR examination, n (%) | |||||||
Known or suspected cardiomyopathy | 147 | (19) | 11 (24) | 136 (18) | 0.32 | ||
Possible coronary disease/vasodilator stress testing | 340 | (43) | 23 (51) | 317 (43) | 0.28 | ||
Evaluation for arrhythmia substrate | 243 | (31) | 7 (16) | 236 (32) | 0.02 | ||
Sarcoidosis | 5 | (0.6) | 0 (0) | 5 (0.7) | 0.58 | ||
Valve disease assessment | 48 | (6) | 3 (7) | 45 (6) | 0.88 | ||
Pericardial disease assessment | 34 | (4) | 2 (4) | 32 (4) | 0.97 | ||
Possible mass or thrombus | 29 | (4) | 3 (7) | 26 (4) | 0.28 | ||
Thoracic aorta assessment | 19 | (2) | 1 (2) | 18 (2) | 0.93 | ||
Medication, n (%) | |||||||
ACEi or ARB | 315 | (40) | 20 | (44) | 295 | (40) | 0.55 |
Antiarrhythmic | 49 | (6) | 6 | (13) | 43 | (6) | 0.04 |
Aspirin or other antiplatelet | 397 | (51) | 31 | (69) | 366 | (50) | 0.01 |
Beta-blockers | 387 | (49) | 34 | (76) | 353 | (48) | < 0.001 |
Loop diuretics | 164 | (21) | 24 | (53) | 140 | (19) | < 0.001 |
Insulin | 121 | (16) | 18 | (44) | 140 | (14) | < 0.001 |
Oral hypoglycemic | 54 | (7) | 6 | (13) | 48 | (7) | 0.08 |
Statin | 315 | (40) | 23 | (51) | 292 | (40) | 0.13 |