Figure 6
From: A simple label-free method reveals bacterial growth dynamics and antibiotic action in real-time
(a) An exponentially growing culture of E. coli ATCC 25922 was cultivated at 37 °C in SLIC in the presence of meropenem (0–32 mg/L), gentamicin (0–1 mg/L) and cefoxitin (0–32 mg/L) in SLIC at 37 °C. Light scattering was detected and plotted in mV against time. Values represent mean and ± 2 standard error. For clarity every 100th data point is plotted. EUCAST MIC for Enterobacteriaceae to these agents is as follows: Meropenem—2-8 mg/L. Gentamicin—2 mg/L, Cefoxitin—8 mg/L. One measurement was taken every second. (b) This represents the percentage inhibition for the organisms reported in (a) but recalculated using the equation (x + 1)/(y + 1) × 100.
