Table 4 Correlation between NSE and pain, delirium, and withdrawal symptoms.

From: Pediatric delirium is associated with increased brain injury marker levels in cardiac surgery patients

Variable

Correlation analysis

p-value

Pain: FLACC behavior scale

Face

0.15

0.17

Legs

0.17

0.11

Activity

0.27

0.01

Consolability

0.06

0.58

Cry

0.31

 < 0.01

Iatrogenic withdrawal syndrome: WAT-1

Any loose /watery stools

0.08

0.46

Any vomiting/wretching/gagging

0.01

0.86

Temperature > 37.8 °C

0.16

0.13

State

0.33

 < 0.01

Tremor

0.09

0.38

Any sweating

0.04

0.71

Uncoordinated/repetitive movement

0.25

0.02

Yawning or sneezing

0.1

0.34

Startle to touch

0.16

0.14

Muscle tone

0.15

0.18

Time to gain calm state

0.24

0.03

Delirium: CAPD

Eye contact

0.55

 < 0.01

Action

0.42

 < 0.01

Aware

0.49

 < 0.01

Communicate

0.25

0.02

Restless

 − 0.07

0.51

Inconsolable

 − 0.003

0.98

Underactive

0.25

0.02

Respond

0.2

0.07

  1. CAPD Cornell Assessment of Pediatric Delirium, FLACC Face, Leg, Activity, Consolability behavioral scale, WAT-1 Withdrawal assessment tool.
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