Figure 12 | Scientific Reports

Figure 12

From: In vivo assessment of mitral valve leaflet remodelling following myocardial infarction

Figure 12

(a) Snapshots of a simulated MV throughout a FE closure simulation, showing initial coaptation by pressurisation followed by shape enforcement using the LCPF, resulting in a locally computed stretch field. The LCPF causes the MV mesh to be pushed locally and orthogonally toward the imaged final configuration, thus enforcing the overall shape without biasing local stretch estimates (see Rego et al.20 for details). (b) Snapshots of a cross section of the simulated mesh, shown for the same time points as in (a); a cross section of the true closed shape (red) is shown for comparison with the final configuration. (c) Coordination of the boundary conditions and loads that are applied during the FE simulation to ensure proper closure and shape enforcement (adapted from Rego et al.20).

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