Figure 6
Effect of IL-1β on GABA current in the absence or presence of IL-10. Bar-graphs show the % variation in IGABA amplitude induced by IL-10 (red bar and trace), IL-1β (green bar and trace) or their combination (grey bar and trace) in oocytes injected with GG tissues (Patients # 8–10; Table 1). Data are expressed as a % variation of the mean current amplitude after the incubation with each cytokine singularly or in combination. Mean current variation was + 31.0 ± 2.6% after IL-10 incubation (100 ng/ml, n = 10), − 19.6 ± 3.15% after incubation with IL-1β (25 ng/ml, n = 10) and − 15.6 ± 3.5% after co-incubation with IL-10 + IL-1β (n = 10) as described in the text. ** p < 0.01 by paired t-test.
