Table 1 Baseline characteristics and comorbidities of the study population.
From: Cardiopulmonary work up of patients with and without fatigue 6 months after COVID-19
Total (n = 60) | Fatigue (n = 17) | No fatigue (n = 43) | p value | |
|---|---|---|---|---|
Characteristics | ||||
Age, years | 61 ± 2 | 59 ± 4 | 61 ± 2 | 0.38 |
Female | 20 (33) | 9 (53) | 11 (26) | 0.06 |
Male | 40 (67) | 8 (47) | 32 (74) | 0.06 |
ARDS | 18 (30) | 4 (24) | 14 (33) | 0.55 |
Symptom onset to, days | ||||
Hospitalization | 7 ± 0 | 8 ± 1.7 | 7 ± 0.8 | 0.25 |
ICU admission | 10 ± 0.6 | 13 ± 2.2 | 9 ± 0.7 | 0.60 |
Inpatient management | ||||
ICU | 24 (40) | 4 (24) | 20 (47) | 0.14 |
Invasive ventilation | 18 (30) | 4 (24) | 13 (30) | 0.75 |
Extracorporeal membrane oxygenation | 3 (5) | 0 (0) | 3 (7) | 0.55 |
Prone positioning | 14 (23) | 2 (12) | 11 (26) | 0.31 |
Dialysis | 8 (13) | 2 (12) | 5 (12) | > 0.99 |
Antibiotic therapy | 23 (38) | 5 (29) | 16 (37) | 0.76 |
Periods, days | ||||
Fever days | 16 ± 2.1 | 16 ± 3 | 17 ± 2.6 | 0.11 |
Hospitalization | 25 ± 2.6 | 22 ± 4.8 | 27 ± 3.4 | 0.16 |
ICU length of stay | 32 ± 2.9 | 36 ± 3.2 | 31 ± 3.7 | 0.58 |
Laboratory findings on admission | ||||
D-dimer [ng/ml] | 1418 [890–4952] | 1128 [983–1273] | 2169 [957–6103] | 0.18 |
LDH [U/l] | 378 [290–458] | 330 [268–445] | 402 [295–458] | 0.82 |
CK [U/l] | 124 [63–327] | 107 [57–297] | 124 [67–351] | 0.53 |
CKMB [U/l] | 19 [16–25] | 17 [16–19] | 22 [15–27] | 0.69 |
hs-Troponin T [pg/ml] | 13 [6–19] | 11 [4–19] | 13 [7–18] | 0.80 |
Creatinine [mg/dl] | 1 [0.8–1.2] | 0.9 [0.9–1.2] | 1 [0.8–1.3] | 0.96 |
CRP [mg/l] | 81 [44–153] | 45 [26–107] | 94[54–159] | 0.69 |
PCT [ng/ml] | 0.1 [0.1–0.3] | 0.1 [0.1–0.1] | 0.2 [0.1–0.4] | 0.32 |
Ferritin [ng/ml] | 1185 [760–2046] | 799 [528–1069] | 1185 [771–2364] | 0.25 |
Comorbidities | ||||
Total | 53 (88) | 16 (94) | 37 (86) | 0.66 |
Arterial hypertension | 31 (52) | 1 (6) | 3 (7) | > 0.99 |
COPD | 8 (13) | 3 (18) | 5 (12) | 0.68 |
Bronchial asthma | 8 (13) | 2 (12) | 6 (14) | > 0.99 |
Pre-existing heart diseases | 13 (22) | 2 (12) | 6 (14) | > 0.99 |
Overweight (BMI ≥ 25 kg/m2, < 30 kg/m2) | 16 (27) | 4 (24) | 12 (28) | > 0.99 |
Obesity (BMI ≥ 30 kg/m2) | 22 (37) | 7 (41) | 15 (35) | 0.76 |
Chronic kidney disease | 9 (15) | 2 (12) | 5 (12) | > 0.99 |
Smoking | ||||
Former smoking | 10 (17) | 5 (41) | 5 (12) | 0.26 |
Current smoking | 9 (15) | 3 (18) | 6 (14) | 0.70 |
Diabetes mellitus | 16 (27) | 4 (24) | 5 (12) | 0.25 |
Malignancy | 12 (20) | 4 (24) | 8 (19) | 0.72 |
Chronic hepatitis | 7 (12) | 2 (12) | 5 (12) | > 0.99 |
Peripheral arterial occlusive disease | 4 (7) | 1 (6) | 3 (7) | > 0.99 |
