Figure 3 | Scientific Reports

Figure 3

From: LncRNA ANRIL-mediated miR-181b-5p/S1PR1 axis is involved in the progression of uremic cardiomyopathy through activating T cells

Figure 3

The regulatory effects of ANRIL/miR-181b-5p on T cell activation in vitro (A) qRT-PCR of ANRIL expression; (B) qRT-PCR of miR-181b-5p expression; (C) CCK-8 assay of cell viability; (D) ELISA of inflammatory parameters (IFN-γ, IL-2, IL-10, and TNF-α); (E) DLR assay of the target relationship between miR-181b-5p and S1PR1; (F) qRT-PCR of ANRIL expression. **P < 0.01, ***P < 0.001 vs. control (A–D,F) or mimic NC (E); ##P < 0.01, ###P < 0.001 vs. activation. Data was analyzed using t test or one-way analysis of variance (ANOVA) followed by Tukey’s test.

Back to article page