Figure 5 | Scientific Reports

Figure 5

From: LncRNA ANRIL-mediated miR-181b-5p/S1PR1 axis is involved in the progression of uremic cardiomyopathy through activating T cells

Figure 5

The effects of ANRIL silencing or miR-181b-5p overexpression on the characteristics of UC in the model mice (A) body weight; (B) serum levels of BUN and Scr; (C) cardiac parameters (LVEDD, LVESD, LVAWS, LVAWD, LVEF, MPI, LVEF/MPI, FS, E/A, and IVRT); (D) serum levels of inflammatory parameters (IFN-γ, IL-2, IL-10, and TNF-α). ***P < 0.001 vs. control; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. model. Data was analyzed using t test or one-way analysis of variance (ANOVA) followed by Tukey’s test.

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