Figure 6

Cell cycle analysis of LNCaP, PC3, 5637, and ACHN cancer cell lines. DNA content of LNCaP, PC3, 5637, and ACHN cancer cell lines was assessed after exposed with exosomes by PI staining. The cell cycle analysis detected G1 area increased in LNCaP, PC3, 5637, and ACHN cell lines when treated with exosomes. The percentages of cells at the G2 phase were concurrently reduced in all treated cells. Therefore, exosomes apparently induce sub G1/G1 arrest in LNCaP, PC3, 5637, and ACHN cell lines.