Figure 2

Impaired chemical nociception in ppk19 mutant larvae. (A) Aversive rolling response of wild-type (w¹¹¹⁸) larvae in acid solution; rolling within 10 s was counted as response. n = 30 for each concentration. Error bars indicate ± SEM of more than three independent experiments. (B-D) Larval rolling in 10% HCl solution; rolling within 10 s was counted as response. n > 45 for each genotype. Error bars indicate ± SEM of more than three independent experiments. One-way ANOVA with Dunnett’s post hoc test used to test for significant differences. **, *** indicates p < 0.01, p < 0.001, respectively.