Figure 3

Impaired mechanical and chemical nociception and larval movement with ppk19 RNAi expression in mdIV neurons. (A) Larval rolling against 45mN force on larval skin; rolling within two s was counted as response. n > 45 for each genotype. (B) Body turns > 40° were counted over a five-minute interval. n > 15 for each genotype. (C-D) Larval rolling in 10% HCl solution; rolling within 10 s was counted as response. n > 45 for each genotype. Error bars indicate ± SEM of more than three independent experiments. One-way ANOVA with Dunnett’s post hoc test was used to test for significant differences. ** and *** indicates p < 0.01, p < 0.001, respectively.