Figure 5 | Scientific Reports

Figure 5

From: Investigation of 91 proteins implicated in neurobiological processes identifies multiple candidate plasma biomarkers of stroke outcome

Figure 5

Selected annotated biological functions for 62 candidate acute and/or 3-month protein markers with either statistically significant or suggestive association with acute stroke severity or neurological outcome. Present annotations according to the Gene Ontology (GO) database18, version released July 1, 2022, doi: 10.5281/zenodo.6799722. Proteins are sorted by hierarchical clustering according to Euclidean distance in the acute phase. Annotations are marked in blue for proteins where lower plasma levels in the acute stroke phase were associated with higher NIHSS scores (worse stroke severity or outcome), and red for proteins for which higher plasma levels were associated with higher NIHSS scores.

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