Table 3 Common and frequent IS6110 locations in the strains studied, grouped by lineage.

From: Analysis of the twenty-six largest outbreaks of tuberculosis in Aragon using whole-genome sequencing for surveillance purposes

 

5’-IS point

3’-IS point

Direct repeat

Gene

Direction

 

L4.3

3,480,373

3,480,371

cag

Rv3113

Forward

100% strains

932,202

932,204

aac

lpqQ:Rv0836c

Reverse

1,987,457

1,986,625

plcD/Rv1754c

Reverse

1,989,080

1,986,625

cut1/Rv1754c

Reverse

1,986,623

1,986,625

aac

Rv1754c

Reverse

1,989,080

1,979,923*

cgc

cut1

Reverse

81.8% strains

1,989,080

1,986,625

cut1/Rv1754c

Reverse

2,633,843

2,633,841

ctc

ppe38

Reverse

45.5% strains

3,665,157*

3,665,159*

caa

MT3426:MT3427

Reverse

91% strains

3,665,159*

3,668,981*

MT3426:MT3427/IS1547

Forward

L4.8

3,668,619*

3,668,723*

MT3429

Forward

100% strains

1,895,651

1,895,654

ccta

Rv1668c:Rv1669

Reverse

1,986,939*

1,986,937*

acc

Rv1762c:Rv1763

Forward

1,979,901*

1,986,937*

cut1/Rv1762c:Rv1763

Forward

2,604,207*

2,604,210*

gaaa

ppe71

Reverse

85.7% strains

889,020

890,375

gagg

Rv0795-Rv0796

Forward

85.7% strains

L4.1.2.1

1,075,948

1,075,950

acc

Rv0963c

Reverse

100% strains

1,986,626

1,986,622

tgttc

Rv1754c

Forward

483,296

483,298

agg

Rv0403c

Reverse

2,610,863

2,610,861

gcc

Rv2336

Forward

3,668,575*

3,668,756*

MT3429

Forward

  1. The IS6110 locations present in all the strains studied belonging to that lineage are in bold, and the frequent locations found are in italic.
  2. *Points referred to the M. bovis genome.