Figure 1

Overall study cohort. First the correlation of rT1/T2 with T1- and T2-relaxation time was investigated by reanalyzing the raw data from ref.16. Then, the study was conducted in two stages, as an exploratory cohort study followed by a validation cohort study to investigate the correlation of rT1/T2 and IDH mutation status of histologically confirmed LrGGs. IDHmt, IDH-mutant; IDHwt, IDH-wildtype; AMUH, Asahikawa Medical University Hospital; OICI, Osaka International Cancer Institute; TCIA/TCGA, Cancer Imaging Archive / Cancer Genome Atlas.