Figure 3
From: Dysregulated thrombospondin 1 and miRNA-29a-3p in severe COVID-19
Correlation between the expression levels of hsa-miR-29a-3p and its two putative target genes in the severe COVID-19 samples. (a) Volcano plots representing differentially expressed miRNAs with the log2-fold change plotted against the negative log10 p-value of the compared groups. Red and blue dots indicate upregulated and downregulated miRNAs, respectively, in the severe COVID-19 samples. (b) Sequence alignments of hsa-miR-29a-3p with human IL17RA or THBS1 mRNA 3′-UTRs. The prediction of binding sites and free energy (ΔG) were obtained from miRWalk 3.0 online prediction software. (c) Scatter plots showing the expression levels of hsa-miR-29a-3p versus IL17RA and THBS1 in all eight subjects. ρ indicates Spearman’s correlation coefficient.
